You can use your existing Medical Independent, MediLearning or PharmacistCPD account to log in.


Medicalindependent.ie is Ireland's only investigative medical news website for doctors, healthcare professionals and anyone with an interest in health issues.

Established in 2010, along with its sister publication The Medical Independent, our stated aim is to investigate and analyse the major issues affecting healthcare and the medical profession in Ireland. The Medical Independent has won a number of awards for its investigative journalism, and its stories are frequently picked up by national digital, broadcast and print media. The Medical Independent is published by GreenCross Publishing.

Address: Top Floor, 111 Rathmines Road Lr, Dublin 6

Tel: 353 (01) 441 0024

GreenCross Publishing is owned by Graham Cooke.


The benefits of registering: only registered users:
  • receive the ecCopy two days prior to the printed edition.
  • have automatic access to our free CPD sites.
  • can partake in our online MCQs.
  • can enter our online sports quiz.

Sign up now for ease of access to The Medical Independent, Ireland’s most frequently published medical newspaper, delivering award-winning news and investigative reporting.

Download the new Mindo app for both IOS & Android.

  • Get notified when a story goes live
  • Access Premium Content
  • Read Offline
 
[the_ad_placement id="main-ldb-public"]
[the_ad_placement id="main-ldb-mobile-public"]

You are reading 1 of 2 free-access articles allowed for 30 days

Irish AMD research showing promise

By Dermot - 27th May 2015 | 9 views

New Irish research on age-related macular degeneration (AMD) is showing potential as regards one day identifying people more likely to develop the condition and the likelihood of having severe disease or being responsive to a particular therapy, the ICO Annual Conference heard.

Dr Maedbh Rhatigan, Researcher, Royal Victoria Eye and Ear Hospital (RVEEH) Research Foundation, gave an update on her research project about the negative regulators of inflammation and AMD in a cohort of patients under the Irish Longitudinal Study on Ageing (TILDA).

Dr Rhatigan was announced as the winner of the ICO/Novartis Bursary research award at the 6th Annual Retinal Meeting last November for her project. AMD is the leading cause of central vision loss worldwide. The estimated prevalence of AMD in Ireland is seven per cent, with an annual cost over €130 million. Inflammation is known to play a role in the development of AMD, however the exact mechanisms remain unresolved. In collaboration with TILDA, Dr Rhatigan’s project is looking at the levels of negative regulators or ‘off switches’ of three key inflammatory mediators, elevated in the blood of people with AMD. To date she has found preliminary evidence that particular negative regulators are elevated in people with AMD.

<blockquote>

Inflammation is known to play a role in the development of AMD, however the exact mechanisms remain unresolved

</blockquote>

“It is early days, and these are preliminary results, but this study will help to further understand the role of inflammation in AMD. It is our understanding these pathways may aid in identification of patients at increased risk of progression to more severe forms of AMD and may provide novel targets for therapeutic intervention,” Dr Rhatigan told <em><strong>MI</strong></em>.

Dr Rhatigan’s study is being carried out under the supervision of Mr Mark Cahill, Consultant Ophthalmologist and Vitreoretinal Surgeon at the RVEEH and Dr Sarah Doyle, Assistant Professor in Immunology at the Department of Clinical Medicine, Trinity College Dublin, and is being undertaken as part of an MSc by research in Clinical Medicine.

Meanwhile, Prof Carrie MacEwen, President of the Royal College of Ophthalmologists in London, gave a presentation on the epidemiological aspects, changing trends and outcomes of ocular trauma, while the conference also featured a well-attended medical retina symposium and an update on oculoplastic management across the ages.

Leave a Reply

[the_ad_placement id="main-ldb-public-2"]
[the_ad_placement id="main-ldb-mobile-public-2"]
Latest Issue
The Medical Independent – 24 June 2021

You need to be logged in to access this content. Please login or sign up using the links below.

[the_ad_placement id="main-mpu-public"]
Most Read
[the_ad_placement id="main-ldb-public-2"]
[the_ad_placement id="main-ldb-mobile-public-2"]